Quick Answer
Colgate Total Advanced Whitening Toothpaste 5.1oz

Colgate Total is the better everyday toothpaste for most people thanks to its stannous fluoride formula that fights bacteria 12 hours after brushing. Crest Pro-Health is the better choice for users who want a more aggressive deep-clean sensation and are buying in multi-packs.

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At a Glance

#ProductAwardPriceOur Score
1
Colgate Total Advanced Whitening Toothpaste 5.1ozColgate Total Advanced Whitening Toothp…
Best Overall $9 9.2 Buy →
2
Colgate Total Teeth Whitening Toothpaste 4.8oz Pack of 4Colgate Total Teeth Whitening Toothpast…
Best Value $19 8.9 Buy →
3
Crest Pro-Health Advanced Antibacterial Protection Toothpaste 4-Pack 5ozCrest Pro-Health Advanced Antibacterial…
Best Crest $14 8.5 Buy →
4
Crest Pro-Health Advanced Deep Clean Mint Toothpaste 5.1ozCrest Pro-Health Advanced Deep Clean Mi…
Deep Clean $4 8.2 Buy →
5
Colgate Total Whitening Toothpaste Paste 5.1oz 4 Pack with FluorideColgate Total Whitening Toothpaste Past…
Premium Formula $15 7.8 Buy →
6
Crest Pro-Health Smooth Formula Toothpaste Clean Mint Pack of 3Crest Pro-Health Smooth Formula Toothpa…
Sensitive Friendly $14 7.5 Buy →

Showing 6 of 6 products

Our Top Pick
Colgate Total Advanced Whitening Toothpaste 5.1oz

Colgate Total Advanced Whitening Toothpaste 5.1oz

$9
at Amazon
Best for: Adults who want Colgate's most complete toothpaste combining whitening, antibacterial action, and sensitivity relief

“Colgate Total is the benchmark multi-benefit toothpaste — 12-hour antibacterial protection, whitening, and sensitivity relief in one tube.”

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What we like

  • Stannous fluoride formula fights bacteria 12 hours after brushing
  • Whitening + antibacterial + sensitivity relief in one tube
  • Clinically proven multi-benefit formula

Watch out for

  • Stannous fluoride can temporarily stain teeth if not rinsed thoroughly
  • Single tube — multi-packs offer better value
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Colgate Total Advanced Whitening is the benchmark multi-benefit toothpaste at under $8 per tube. The stannous fluoride formula is clinically proven to fight bacteria for 12 hours after you stop brushing — far beyond what basic sodium fluoride provides. Whitening action gradually lifts surface stains with consistent use. The sensitivity relief layer makes it comfortable enough for twice-daily use even for users with mild sensitivity. One tube handles cavity protection, gum health, whitening, and sensitivity — you don't need separate products.

Best Budget
Colgate Total Teeth Whitening Toothpaste 4.8oz Pack of 4

Colgate Total Teeth Whitening Toothpaste 4.8oz Pack of 4

$19
at Amazon
Best for: Households that go through toothpaste quickly and want Colgate Total whitening at the best per-tube price

“Best value Colgate — the Total Whitening 4-pack gets Colgate's multi-benefit formula at under $4 per tube.”

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What we like

  • 4-pack at under $4 per tube is exceptional value
  • Whitening formula removes surface stains over time
  • Stannous fluoride for antibacterial protection

Watch out for

  • 4-pack requires storage space
  • Whitening results take 2-4 weeks of consistent use
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The Colgate Total Whitening 4-Pack delivers the same stannous fluoride formula at under $4 per tube — a significant savings vs. single-tube purchases. For households that brush twice daily, a 4-pack lasts 4–6 months. The whitening formula removes surface stains consistently. Ideal for anyone who's already tried Colgate Total and wants to stock up at the best price.

Worth Considering
Crest Pro-Health Advanced Antibacterial Protection Toothpaste 4-Pack 5oz

Crest Pro-Health Advanced Antibacterial Protection Toothpaste 4-Pack 5oz

$14
at Amazon
Best for: Families who want an economy-size supply of Crest's best antibacterial toothpaste

“Crest Pro-Health Advanced in a 4-pack — antibacterial fluoride formula at the best per-tube price.”

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What we like

  • 4-pack offers excellent value per tube
  • Antibacterial formula fights gingivitis and plaque
  • Fluoride protects against cavities and strengthens enamel

Watch out for

  • Multi-pack only — not sold as single tube at this price
  • Mint Burst scent not available in other variants at 4-pack
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Crest Pro-Health Advanced in a 4-pack provides Crest's leading stannous fluoride formula at the best per-tube value. The antibacterial formula fights plaque and gingivitis, and the pack format reduces reorder frequency. For users who specifically prefer Crest's texture and clean-mouth sensation over Colgate's formula, this is the most economical entry point.

Worth Considering
Crest Pro-Health Advanced Deep Clean Mint Toothpaste 5.1oz

Crest Pro-Health Advanced Deep Clean Mint Toothpaste 5.1oz

$4
at Amazon
Best for: Adults who want Crest's most thorough clean with strong antibacterial action in a single tube

“Crest's deep-clean flagship — Pro-Health Advanced in a 5.1oz tube with the brand's most complete oral care formula.”

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What we like

  • Targets plaque bacteria below the gumline
  • Deep clean mint flavor leaves a fresh sensation
  • ADA-accepted for cavity protection and gingivitis prevention

Watch out for

  • Single tube — slightly higher per-oz cost than multi-packs
  • Deep Clean formula may feel intense for sensitive users
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Crest Pro-Health Advanced Deep Clean is the most aggressive daily Crest formula. The targeting of plaque bacteria below the gumline makes it a strong pick for users with chronic gum issues. ADA-accepted for both cavities and gingivitis prevention. The Deep Clean sensation is noticeably more intense than standard formulas — this is a plus for heavy coffee/tea drinkers who want a clean that 'feels' thorough.

Best Premium
Colgate Total Whitening Toothpaste Paste 5.1oz 4 Pack with Fluoride

Colgate Total Whitening Toothpaste Paste 5.1oz 4 Pack with Fluoride

$15
at Amazon
Best for: Users who want Colgate's latest-generation Total formula with advanced plaque reduction in a value pack

“Colgate Total's newest formula — 5X plaque bacteria reduction vs. regular fluoride in a 4-pack.”

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What we like

  • Advanced formula reduces plaque bacteria by 5X vs. regular fluoride toothpaste
  • 4 tubes for fewer reorders
  • Mint flavor freshness throughout the day

Watch out for

  • Newer formula — slightly higher price per tube than original Total 4-pack
  • Paste texture vs. gel texture is personal preference
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Colgate Total's latest formula achieves 5X plaque bacteria reduction compared to regular fluoride toothpaste according to Colgate's clinical data. The 4-pack format provides value and reduces reorder frequency. Paste texture foams slightly more than gel variants. For users who want Colgate's most up-to-date antibacterial research in a multi-pack, this is the choice.

Reviewed
Crest Pro-Health Smooth Formula Toothpaste Clean Mint Pack of 3

Crest Pro-Health Smooth Formula Toothpaste Clean Mint Pack of 3

$14
at Amazon
Best for: Users with mild sensitivity who want Crest's gentle everyday formula in a cost-saving 3-pack

“Crest Pro-Health for everyday gentleness — the Smooth Formula 3-pack is the best Crest pick for twice-daily routine use.”

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What we like

  • Smooth formula is gentle enough for daily use twice daily
  • Pack of 3 reduces reordering frequency
  • Non-abrasive gentle clean suitable for sensitive teeth

Watch out for

  • Smooth formula less aggressive than Deep Clean variants
  • Pack of 3 is bulkier to store
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Crest Pro-Health Smooth is the right Crest pick for users with mild sensitivity who find Deep Clean too intense. The non-abrasive formula provides Crest's standard cavity and gingivitis protection without the harsh scrubbing sensation. The 3-pack format offers a middle ground between single tubes and 4-packs for trying the Smooth formula commitment-free at modest cost.

Crest vs. Colgate Toothpaste (2026) Buying Guide

Crest vs. Colgate Toothpaste (2026): Which Brand Cleans Better?

Our Top Pick

Colgate Total Advanced Whitening Toothpaste is our top pick for whitening toothpastes — its 12-hour antibacterial protection, fluoride formula, and proven whitening action address both cavity prevention and cosmetic results in one tube. For budget shoppers, Colgate Total Teeth Whitening Toothpaste 4-Pack offers the same trusted Colgate Total formula in a multi-pack that cuts your per-tube cost significantly.

## How to Choose Between Crest and Colgate Toothpaste Fluoride type matters more than the brand name. Both brands offer sodium fluoride and stannous fluoride options. Stannous fluoride (found in Colgate Total and Crest Pro-Health) fights bacteria, reduces gingivitis, and provides sensitivity relief — standard sodium fluoride does not. If you're choosing between the two, pick a stannous fluoride formula from either brand over a basic formula. Multi-pack economics. Toothpaste is a commodity purchase — price per tube matters. At full price, Colgate Total 4-packs land at under $4/tube; Crest Pro-Health 4-packs are similar. Single-tube formats cost $7–$9 each. Buy multi-packs unless you're sampling a new formula. Sensitivity vs. whitening. Crest Pro-Health Smooth is the gentler pick for sensitivity. Colgate Total Whitening adds surface stain removal. Neither replaces a whitening treatment (like Crest 3D Whitestrips) for significant discoloration. Gel vs. paste. Both brands offer gel and paste variants of their core lines. The cleaning effectiveness is identical — this is purely a texture preference. Paste tends to foam slightly more; gel tends to feel cleaner after rinsing. Children and fluoride. For kids under 3, use a rice-sized amount. For ages 3–6, a pea-sized amount. The ADA recommends fluoride toothpaste for all ages. Both Crest and Colgate make kids' fluoride formulas, but adult Crest/Colgate is fine for children 6+ with supervised brushing.

Related Guides

The Difference Between Colgate and Crest
The Difference Between Colgate and Crest

Bottom Line on the Crest vs. Colgate Decision

Colgate Total Vs. Crest? - The Pro Dentist
Colgate Total Vs. Crest? - The Pro Dentist

For cavity prevention: either brand with fluoride (1000-1450 ppm) is clinically effective. For gum health: stannous fluoride (Colgate Total, Crest Pro-Health) provides anti-gingivitis benefit that sodium fluoride alone doesn't. For sensitivity: either brand's sensitivity line (Colgate Sensitive, Crest Sensi-Stop Strips) uses potassium nitrate or stannous fluoride for different mechanisms — try both if one doesn't work for you within 4 weeks.

Who should pay attention to the comparison: Anyone with diagnosed gingivitis (choose a stannous fluoride formula), significant sensitivity (try both mechanisms), or whitening goals (Crest 3D Whitestrips outperform in-toothpaste whiteners from either brand). For everyone else, the choice between Crest and Colgate is largely flavor preference at the same fluoride concentration.

Colgate Total Advanced Whitening Toothpaste 5.1oz
Colgate Total Advanced Whitening Toothpaste 5.1oz
$9.20
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Common mistake: Using whitening toothpastes containing abrasives daily for years — aggressive abrasive whitening pastes (high RDA) erode enamel over time. Check the Relative Dentin Abrasivity (RDA) score: below 70 is safe for daily use; above 150 is high-abrasion. Most whitening pastes fall in the 100-150 range — fine occasionally, not for twice-daily permanent use.

Watch Before You Buy

Frequently Asked Questions

Is Crest or Colgate better for whitening?
For whitening toothpaste, Colgate Total Whitening and Crest Pro-Health both remove surface stains gradually. Neither dramatically whitens teeth — for noticeable whitening, use Crest 3D Whitestrips or professional treatment alongside your daily toothpaste.
What is stannous fluoride and why does it matter?
Stannous fluoride is a more advanced fluoride compound that fights cavity-causing bacteria, reduces gingivitis, and helps with sensitivity — not just cavity prevention. Both Colgate Total and Crest Pro-Health use stannous fluoride. Most basic toothpastes use sodium fluoride, which only protects against cavities.
Is Colgate Total safe for daily use?
Yes. Colgate Total has been ADA-accepted for decades and is clinically tested for twice-daily use. The stannous fluoride formula has been extensively studied and approved as safe.
Can I use Crest or Colgate with an electric toothbrush?
Yes, both work with any toothbrush. Electric toothbrush users often prefer a slightly lower-foaming formula — the Pro-Health Smooth (Crest) or Total Clean Mint Paste (Colgate) are good choices because they foam less.
Which toothpaste is better for gum health?
Both Crest Pro-Health and Colgate Total are clinically proven to improve gum health and reduce gingivitis. Colgate Total's 12-hour antibacterial protection has broader study coverage. If gum health is the primary concern, either is a solid choice over any basic fluoride toothpaste.
Is the Colgate hum electric toothbrush worth it?
The Colgate hum is a budget smart toothbrush with app tracking. At $140 it's considerably more expensive than Oral-B and Philips Sonicare entry models that offer the same or better vibration performance. It's fine for kids or light users wanting a smart brush on a budget.

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