Quick Answer
Greenies Original Dental Dog Treats Large 36oz 24 Count

Greenies are the gold standard for dog dental treats — VOHC-approved, most clinically validated tartar reduction available in treat form.

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At a Glance

#ProductAwardPriceOur Score
1
Greenies Original Dental Dog Treats Large 36oz 24 CountGreenies Original Dental Dog Treats Lar…
Best Overall $36 9.2 Buy →
2
Pedigree Dentastix Large Dog Treats Fresh Flavor 28 TreatsPedigree Dentastix Large Dog Treats Fre…
Best Daily $14 8.9 Buy →
3
Zuke's Mini Naturals Soft Dog Treats, Chicken Recipe, 16 ozZuke's Mini Naturals Soft Dog Treats, C…
Best Training Size $14 8.5 Buy →
4
Blue Buffalo BLUE Bits Natural Soft-Moist Training Treats Chicken 9ozBlue Buffalo BLUE Bits Natural Soft-Moi…
Best Value $9 8.2 Buy →

Showing 4 of 4 products

Our Top Pick
Greenies Original Dental Dog Treats Large 36oz 24 Count

Greenies Original Dental Dog Treats Large 36oz 24 Count

$36
at Amazon
Best for: Large dogs needing VOHC-accepted daily dental treat for plaque control

“Greenies Large dental treats combine meaningful tartar reduction with a flavor most dogs find irresistible. Daily use during brushing-resistant dog ownership is genuinely effective.”

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What we like

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Greenies Original Dental Dog Treats ($36.97 for 36oz) are the benchmark in canine dental care. The VOHC seal certifies clinical proof of tartar and plaque reduction — meaning Greenies went through actual trials demonstrating measurable improvement. The texture is designed to clean down to the gum line as dogs chew. The treat fully flexes and compresses during chewing rather than shattering (which does not clean teeth). Fully digestible — a significant safety advantage over rawhide. Available in multiple sizes matched to dog weight. For dogs with moderate tartar buildup, daily Greenies combined with annual professional cleaning is a strong maintenance regimen.

Full Specs & Measurements
Upc014891420984
AsinB006W6YHV4
FlavorOriginal
OccasionChristmas
Pet TypeDog
Item FormBone
Brand NameGreenies
Unit Count36.0 Ounce
Item Weight36 Ounces
ManufacturerMars Petcare US
Model Number10096457
Container TypePouch
Dog Breed SizeLarge
Item Type NameDog Natural Dental Treats
Target SpeciesDog
Number Of Items1
Product BenefitsPromotes oral health and fresh breath
Best Sellers Rank#83 in Pet Supplies (See Top 100 in Pet Supplies) #15 in Dog Treat Cookies, Biscuits & Snacks
Additional FeaturesUnique textured surface that cleans down to the gumline
Special IngredientsWheat flour, Gelatin, Glycerin, Natural poultry flavor
Allergen InformationRawhide-Free
Breed RecommendationLarge Breeds
Warranty DescriptionLimited
Age Range DescriptionAdult
Animal Food Diet TypeVeterinary Diet
Manufacturer Part Number10096457
Specific Uses For ProductDental Care
Animal Food Ingredient ClaimNo Artificial Flavors
Recommended Uses For ProductDental Care, Oral Hygiene
Global Trade Identification Number00642863101069
Also Excellent
Pedigree Dentastix Large Dog Treats Fresh Flavor 28 Treats

Pedigree Dentastix Large Dog Treats Fresh Flavor 28 Treats

$14
at Amazon
Best for: Budget-conscious owners wanting affordable daily dental sticks for large dogs

“A budget-friendly daily dental chew that most dogs accept willingly. The fresh flavor adds odor benefit even if the mechanical cleaning is less thorough than toothbrushing.”

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What we like

Watch out for

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Pedigree Dentastix Large Dog Treats ($14.98 for 2-packs) are the widely available daily dental routine option. The star-shaped cross-section texture provides abrasive cleaning action across multiple tooth surfaces. Clinically tested with measurable tartar reduction. Each Dentastix is sized for daily feeding based on body weight. The low cost per treat makes the daily routine affordable for large dogs. Not VOHC-certified but have substantial clinical data behind them. The fresh flavor variant includes added mint for breath freshening alongside mechanical cleaning.

Full Specs & Measurements
Upc023100139845
AsinB007E9VDF6
FlavorMint
OccasionBirthday, Christmas
Pet TypeDog
Item FormBone
Brand NamePedigree
Item Shapex-shape
Unit Count28.0 Count
Item Weight1.5 Pounds
ManufacturerMars Petcare US
Model Number10162377
Container TypeBag
Dog Breed SizeLarge
Item Type NamePEDIGREE DENTASTIX Large Dental Dog Treats Fresh, 1.52 lb. Pack (28 Treats)
Target SpeciesDog
Number Of Items1
Product BenefitsPromotes dental health and fresh breath
Best Sellers Rank#15 in Pet Supplies (See Top 100 in Pet Supplies) #3 in Dog Treat Cookies, Biscuits & Snacks
Additional FeaturesNot-Applicable
Included ComponentsPedigree Dentastix Fresh - Large (28 Treats)
Special IngredientsGreen Tea Extract, Eucalyptus Oil
Allergen InformationAbalone Free
Breed RecommendationLarge Breeds
Age Range DescriptionAdult
Animal Food Diet TypeVeterinary Diet
Manufacturer Part Number10162377
Specific Uses For ProductDental Care
Recommended Uses For ProductDental Care
Animal Food Nutrient Content ClaimNo Added Sugar
Global Trade Identification Number00023100139845
Worth Considering
Zuke's Mini Naturals Soft Dog Treats, Chicken Recipe, 16 oz

Zuke's Mini Naturals Soft Dog Treats, Chicken Recipe, 16 oz

$14
at Amazon
Best for: Positive reinforcement training — low-calorie, high-reward

“Zuke's Mini Naturals are the professional trainer's go-to treat — 3 calories per piece lets you reward 50+ times in a session without caloric blowout, and dogs respond with genuine enthusiasm every ti”

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What we like

  • 3-calorie treats — ideal for training frequency
  • Moist and soft texture dogs go crazy for
  • No corn, wheat, or soy fillers
  • Made in the USA
  • Small pea-sized size perfect for repetition training

Watch out for

  • 16 oz bag empties fast during intensive training
  • Natural preservatives mean shorter shelf life once opened
  • Some sensitive dogs react to the natural flavorings
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Read Full Analysis

Zuke's Mini Naturals Chicken Recipe Dog Training Treats ($14.94) serve a different purpose on this list — they are soft training treats rather than dental treats, included here because many owners use a combination of dental treats for oral health and soft treats for training. Zuke's Minis are 3-calorie treats ideal for reward-based training without disrupting diet. Made with real chicken, blueberries, and carrots. Soft texture that most dogs find highly motivating. Resealable bag. Use alongside a proper dental treat for complete oral care.

Full Specs & Measurements
Upc613423000191
AsinB000H0ZJHW
FlavorChicken
OccasionTreat
Item FormBites, Bits, Tender, Soft
Brand NameZuke's
Unit Count16 Ounce
Item Weight16 Ounces
ManufacturerMerrick Pet Care
Model Number00613423331219
Container TypeBag
Dog Breed SizeSmall
Item Type NameZuke's Mini Naturals Training Dog Treats
Target SpeciesDog
Number Of Items1
Product BenefitsSoftening,Moisturizing
Best Sellers Rank#266 in Pet Supplies (See Top 100 in Pet Supplies) #48 in Dog Treat Cookies, Biscuits & Snacks
Additional FeaturesCorn Free, No Artificial Colors, No Artificial Flavors, Soy Free, Wheat Free
Included ComponentsOne (1) 16 oz Bag - Zuke's Mini Naturals Training Dog Treats Chicken Recipe
Special IngredientsChicken
Allergen InformationAllergen-Free
Breed RecommendationSmall Breeds
Warranty DescriptionWarranty
Age Range DescriptionAll Life Stages
Animal Food Diet TypeVeterinary Diet
Manufacturer Part Number33021
Specific Uses For ProductTraining
Recommended Uses For ProductDog Training
Global Trade Identification Number00613423000191
Best Budget
Blue Buffalo BLUE Bits Natural Soft-Moist Training Treats Chicken 9oz

Blue Buffalo BLUE Bits Natural Soft-Moist Training Treats Chicken 9oz

$9
at Amazon
Best for: Puppies and dogs in active training needing soft bite-sized chicken treats

“Soft, real-chicken training treats that work reliably for reinforcement-based training. The small size and resealable bag make them convenient for clicker or marker training sessions.”

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What we like

Watch out for

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Read Full Analysis

Blue Buffalo BLUE Bits Natural Soft-Moist Training Treats ($9.98) are also in the training treat category — small, soft, high-value rewards for positive reinforcement. Made with real chicken and no by-product meals, corn, wheat, or soy. At 3.5 calories per treat, these can be given frequently during training without causing weight gain. The soft texture is preferred by puppies and seniors with sensitive teeth. Not a dental treat, but a quality nutritional choice for the training portion of your dog's routine.

Full Specs & Measurements
Upc840243116652
AsinB018LN56CY
FlavorChicken
OccasionBirthday
Item FormTreats
Brand NameBlue Buffalo
Unit Count1 Pouch
Item Weight0.59 Pounds
ManufacturerBlue Buffalo Company, Ltd
Model Number802899
Container TypeBag
Dog Breed SizeMedium
Item Type NameBlue Buffalo BLUE Bits Natural Soft-Moist Training Dog Treats
Target SpeciesDog
Number Of Items1
Product BenefitsHealthy, tasty training and treating option
Best Sellers Rank#183,598 in Pet Supplies (See Top 100 in Pet Supplies) #5,017 in Dog Treat Cookies, Biscuits & Snacks
Additional FeaturesSoft-Moist Texture, DHA for Cognitive Development
Special Ingredientschicken, oatmeal, brown rice, fish oil, flaxseed
Allergen InformationChicken Meat
Breed RecommendationLarge Breeds, Medium Breeds
Age Range DescriptionAdult
Animal Food Diet TypeVeterinary Diet
Manufacturer Part Number802899
Specific Uses For ProductActive
Animal Food Ingredient ClaimNo Artificial Colors
Recommended Uses For ProductTraining
Global Trade Identification Number00840243116652

Dog Dental Treats Buying Guide

Best Dog Dental Treats 2026: Greenies, Rawhide & StickPhoto by RDNE Stock project / Pexels

Quick Verdict: Our top pick is the Greenies Original Dental Dog Treats Large 36oz 24 Count (Best Overall) — Greenies Original Dental Treats Large 36oz $36.97 — VOHC approved, proven tartar/plaque reduction, most effective den.... Priced at $36.97.

Budget Pick: The Blue Buffalo BLUE Bits Natural Soft-Moist Training Treats Chicken 9oz at $9.98 — Blue Buffalo BLUE Bits Training Treats $9.98 — soft bite-size treats for training, grain-free formula..

Great for: Dog owners who want easy daily dental hygiene without brushing, and anyone reducing plaque buildup between vet cleanings

Greenies Original Dental Dog Treats Large 36oz 24 Count
Greenies Original Dental Dog Treats Large 36oz 24 ...
$36.97
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Not ideal if: Your dog has severe dental disease — chews are maintenance, not treatment; a vet cleaning is the required first step

Dog dental treats work by mechanical abrasion during chewing — the texture scrubs against tooth surfaces. Look for VOHC (Veterinary Oral Health Council) approval, which requires clinical proof of plaque and tartar reduction. Size matters: treats sized too small pass through without adequate chewing time; too large and dogs gulp them. Most treats are given daily and sized by body weight. Rawhide-free options are safer for dogs prone to gulping large pieces. For dogs with dental disease already present, consult your vet — treats prevent buildup but do not reverse existing disease. Dental treats supplement but do not replace professional cleanings for dogs with significant tartar. Choosing the right food starts with knowing how to read the label — our complete pet food label guide decodes AAFCO statements, ingredient lists, and marketing language.

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Common Mistakes

Treating dental chews as a substitute for brushing is the biggest mistake — no treat cleans teeth as effectively as a toothbrush. Dental treats are a supplement to brushing, not a replacement. Second, many owners buy the wrong size; always verify the weight range on the package matches your dog. Finally, hardness matters: treats labeled "hard" (like antlers or bully sticks) can fracture teeth — the "fingernail test" applies here too: if you can't dent the treat with your thumbnail, it's too hard for tooth safety.

Price Context

Pet Honesty Dental Powder Exposed: Science or Sprinkle Psych
Pet Honesty Dental Powder Exposed: Science or Sprinkle Psychology? (20

Budget dental treats (Pedigree DentaStix, Milk-Bone Brushing Chews) run $0.30–$0.60 per treat. Greenies, the VOHC-approved standard, run $1.50–$2.50 per treat for large dogs, or $30–$40 for a monthly supply. The premium is significant but Greenies is the most consistently vet-recommended option for owners who won't brush their dog's teeth daily.

Pedigree Dentastix Large Dog Treats Fresh Flavor 28 Treats
Pedigree Dentastix Large Dog Treats Fresh Flavor 2...
$14.98
See Full Review →

Frequently Asked Questions

Do dog dental treats actually work?
VOHC-approved treats (Greenies, Pedigree Dentastix) have clinical evidence of plaque/tartar reduction. Generic dental bones without VOHC approval lack this validation.
How often should I give my dog dental treats?
Daily is ideal for maximum benefit. Most treats are sized for once-per-day feeding and included in the daily calorie count.
Are Greenies safe for dogs?
Yes — Greenies are digestible and have a long safety record. Supervise dogs during the first few chews if they are gulpers. Match size to your dog's weight.
What is the VOHC seal?
The Veterinary Oral Health Council seal certifies that a product has proven in clinical trials to reduce plaque, tartar, or both by at least 10% compared to a control. It is the gold standard for dental health claims.
Can dental treats replace teeth brushing?
No — brushing is the most effective dental hygiene method. Treats are a valuable supplement, especially for dogs who resist brushing, but the ideal is both.

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Prices shown reflect Amazon pricing at the time this page was last generated. Click “See Today’s Price” to get the current live price on Amazon. Read our full methodology →

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